Журнал прикладной фармации
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ISSN: 1920-4159
ISSN: 1920-4159
Deepika B*, Samreen Fatima, Md Naser, Syed Mohammed Nasir, Mohd Shoaib Afrose, P. Ravi Teja
This research provides knowledge about a novel herbal transdermal patch preparation (transdermal patch) useful in treatment of arthritis. Formulation comprises of plant extract as anti-artheritic with synthetic polymers. The main aim of the study is to evaluate, optimize and evaluate transdermal patch of Tinospora cardifolia extract (Tce) by the combination of different synthetic polymers and to release the drug in a controlled manner. Transdermal patches were often formulations was developed by solvent evaporation technique by the combination of Eudragit L-100 and HPMC as rate controlling (release retardants) polymer with different concentrations. Formulation F9 showed maximum bioavailability and maximum release i.e., 100.19% ± 0.34% within 6 h and it is said to be ideal combination for controlling the release. It has been surprisingly found that a transdermal delivery patch comprising this composition, or matrix layer, can effectively delivers biologically active compounds.