Журнал термодинамики и катализа
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ISSN: 2157-7544
ISSN: 2157-7544
Abiye Tigabu
Introduction: Staphylococcus aureus is a Gram positive, catalase positive and coagulase positive bacterial species commonly found on the skin and in the nose of most healthy individuals. The anterior nares of nose are the most frequent carriage sites for S. aureus in both adults and children. Methicillin resistance among S. aureus isolates has steadily increased worldwide. Objective: The main objective of this study was to determine nasal carriage rate, antimicrobial susceptibility pattern and associated risk factors of Staphylococcus aureus with special emphasis on MRSA among urban and rural elementary school children in Gondar, Northwest Ethiopia. Method: A community based comparative cross sectional study was conducted on 622 urban and rural elementary school children in Gondar from January 1st to March 30th, 2018. Data was collected using a questionnaire and nasal swab samples were collected by sterile cotton tip swab moistened with sterile normal saline. Collected samples were inoculated on mannitol salt agar and incubated aerobically at 37oC for 24hrs. S. aureus was confirmed by observing colony characteristics and biochemical tests. MRSA was detected using cefoxitin disc by Modified Kirby Bauer disk diffusion technique. Finally data was entered, cleared and checked using Epi-info version 7 and exported to SPSS version 20 for analysis. Odds ratio and logistic regression were used for statistical association. P-value < 0.05 at 95% CI was considered for statistical association.