Вирусология и микология
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Transmission of Zika Virus

Bin Gotoh

Zika infection has a place with the family Flaviviridae and the variety Flavivirus, along these lines is identified with the dengue, yellow fever, Japanese encephalitis, and West Nile infections. Like other flaviviruses, Zika infection is encompassed and icosahedral and has a nonsegmented, single-abandoned, 10 kilobase, positive-sense RNA genome. It is most firmly identified with the Spondweni infection and is one of the two known infections in the Spondweni infection clade.
Cross-part of Zika infection, demonstrating the viral envelope made out of envelope proteins (red) and layer proteins (purple) installed in the lipid film (white): The capsid proteins (orange) are indicated associating with the RNA genome (yellow) at the focal point of the virus.
A positive-sense RNA genome can be straightforwardly converted into viral proteins. As in other flaviviruses, for example, the comparably measured West Nile infection, the RNA genome encodes seven nonstructural proteins and three primary proteins. One of the underlying proteins exemplifies the infection. This protein is the flavivirus envelope glycoprotein that ties to the endosomal layer of the host cell to start endocytosis. The RNA genome shapes a nucleocapsid alongside duplicates of the 12-kDa capsid protein. The nucleocapsid, thusly, is encompassed inside a host-determined film altered with two viral glycoproteins. Viral genome replication relies upon the creation of twofold abandoned RNA from the single-abandoned, positive-sense RNA (ssRNA(+)) genome followed by record and replication to give viral mRNAs and new ssRNA(+) genomes.