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Breif note on Complex Pathogenesis of Cancer

Melifan Sorinshu*

Cancer, often referred to as the "emperor of all maladies," is a formidable adversary that affects millions of lives worldwide. It is a complex group of diseases characterized by the uncontrolled growth and spread of abnormal cells in the body. While the word "cancer" may could cause emotions of fear and uncertainty, understanding its pathogenesis is a important step towards improving prevention, early detection, and treatment strategies. At its core, cancer begins with genetic mutations, which can be inherited or acquired over time due to exposure to carcinogens, radiation, or errors in DNA replication. These mutations disrupt the normal regulatory mechanisms that govern cell division, leading to the formation of malignant tumors. Inflammation, a key contributor to cancer, can promote cell survival, angiogenesis, and metastasis. Additionally, hormonal imbalances, viral infections, and chronic inflammation can further fuel carcinogenesis.