Анестезия и клинические исследования

Анестезия и клинические исследования
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ISSN: 2155-6148


Comparison of Benzydamine Hydrochloride Mouthwash and Intravenous Dexamethasone in Reducing Sore Throat and Hoarseness after Using i-gel™ Laryngeal Mask Airway

Syafri Kamsul Arif

One of complications following surgery under general anesthesia using Laryngeal Mask Airway (LMA) is sore throat (ST) and hoarseness. The aim of this study was to compare 22.5 mg Benzydamine HCl (BH) and 0.2 mg/kg intravenous (iv) Dexamethasone in reducing postoperative ST and hoarseness in patients underwent elective surgery under general anesthesia (GA) using i-gel™ LMA. A total of 48 adult, ASA PS 1-2, aged 18-65 years, Mallampati classification 1 and 2, mouth opening >3 cm, and BMI 18.5-25 kg/cm2 patients who underwent elective surgery with GA using i-gel™ LMA included and randomized into two groups. The first group (group A) received 22.5 mg BH 15 ml over 1 minute and the second group (group B) received 0.2 mg/kg iv Dexamethasone 30 minutes before inserted i-gel™ LMA. ST and hoarseness were assessed before surgery in preparation room (T0) and at 1 hour (T1), 6 hours (T2), 12 hours (T3), and 24 hours (T4) post LMA exertion. 22.5 mg BH mouthwash was more effective in reducing ST and hoarseness in patients after using i-gel™ LMA compared to 0.2 mg/kg iv Dexamethasone at T3 post LMA exertion.