Клиническая и экспериментальная кардиология
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Coronary Artery Lesions in a Young Patient with Kawasaki Disease from Pacific Region

N John Camm 1*, Erhan Tenekecioglu 2, Ahmed Kamel 3, Francisco J Somoza-Cano 4, Danilo Maksud 5, Julia Ramírez García6

Kawasaki disease is well known and widely prevalent acute febrile illness and systemic vasculitis of unknown aetiology that usually and predominantly afflicts children of younger age group usually below 5 years. Its coronary presentations are usually coronary artery aneurysms and can result in long-term cardiovascular sequelae. Kawasaki disease is the leading cause of acquired heart disease among children in the Pacific region. Sometimes coronary artery aneurysms developed in some untreated children with Kawasaki disease, might lead to ischaemic heart disease and myocardial infarction. Early treatment with Intravenous Immunoglobulin (IVIG) might reduce the risk of development of coronary artery aneurysms, several cases have been reported to have IVIG resistant Kawasaki disease and are at increased risk of developing coronary artery damage. Besides, lack of specific diagnostic tools and biomarkers for Kawasaki disease make early diagnosis and treatment challenging. Though Kawasaki Disease is prevalent in more than 60 countries, including Asia, the Middle East, Latin America, and Africa, as well as in North America and Europe it still found centered on Japan in Pacific region. Coronary involvement is a common and most serious complication that usually presents in later stage of disease progression. The purpose of this review is to report a case of Kawasaki Disease and describe the coronary presentation of Kawasaki Disease.