Анатомия и физиология: текущие исследования

Анатомия и физиология: текущие исследования
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ISSN: 2161-0940

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Influx and Efflux of Immune Cells in the Central Nervous System

Fujita M, Omura S, Sato F, Park AM and Tsunoda I

The influx and efflux of immune cells in the central nervous system (CNS) have long remained to be unclear. In this regard, we have addressed this issue using animal models of CNS tumors and experimental autoimmune encephalitis (EAE) that is relevant to multiple sclerosis (MS) in human. For immune cells to migrate into brain parenchyma, chemokines play central roles. In contrast, when immune cells exit the brain parenchyma, lymphatic system plays central roles. Most recently, the relationship between the CNS immunology and gut microbiome is being addressed using the same systems.

Отказ от ответственности: Этот тезис был переведен с использованием инструментов искусственного интеллекта и еще не прошел рецензирование или проверку.
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