Гинекология и акушерство

Гинекология и акушерство
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ISSN: 2161-0932


Live Birth after In Vitro Maturation of Oocytes in a Patient with Repeated Fertilization Failure in IVF: A Case Report

Smirnova A, Anshina M, Sergeev S and Ellenbogen A

The incidence of fertilization failure has decreased dramatically since the intracytoplasmic sperm injection procedure (ICSI) was successfully introduced into clinical practice. However, even in very successful units with remarkable pregnancy rates, there are couples who face repeated in vitro fertilization (IVF) failure due to low or absence of fertilization. We present a case of a 36-year-old woman with tubal factor of infertility and two previous IVF attempts with short and long agonist protocols and absence of normal fertilization after ICSI. The third cycle performed with in vitro maturation of oocytes (IVM) led to the development of top quality embryos. Two transferred embryos ensued in a singleton pregnancy and term delivery of a healthy girl.