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NAC (N-acetylcysteine) Research Review: Safe, Effective,Timely

Lanika Buchanan

 NAC or N-acetylcysteine is a safe, inexpensive and impressively versatile supplement. It is a powerful antioxidant and should be considered in treating conditions characterized by inflammation in the formation of free oxygen radicals. It stimulates the production of glutathione which is considered the “mother antioxidant”. NAC appears to protect the endothelial cells by decreasing mitochondrial membrane depolarization and increasing intracellular glutathione. There is evidence of benefit in a variety of conditions including polycystic ovarian syndrome, chronic bronchitis (1, 2,3),cystic fibrosis, infertility (4,5,6), acetaminophen toxicity (3), ulcerative colitis (1), Alzheimer’s (7,8), Parkinson’s(9), cancers (lung, liver and colon) and asthma(11, 12, 13).