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Rapidly progressive fatal respiratory failure by human metapneumovirus infection in a 2-year-old girl and review of the literature

Yumie Tamura, Saori Amano, Kazuaki Matsumoto, Hisae Nakatani, Miho Ashiarai, Keiko Onda, Mari Okada, Masako Imai, Natsuko Suzuki, Akihiro Oshiba, Masayuki Nagasawa

Human metapneumovirus (hMPV) was discovered in 2001 and it is one of the common viruses that cause respiratory infection in infants, which is usually self-limiting in nature. We report a 2-year-old girl with hMPV infection, who was dead of respiratory failure in a rapidly progressive clinical course. We discuss about the clinical and biological features of hMPV infection with a review of the literature.