Журнал гематологии и тромбоэмболических заболеваний
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Red Blood Cell Transfusion in Palliative Care Patients with Oncohematological Disease

Mariana Munari Magnus*, Julia Crosariol Lindenberg Lacativa, Jackeline Androlage Assumpção

Red blood cell transfusion in oncohematological patients is considered an essential part of treatment, but its role in palliative care that aims to improve symptoms and quality of life is not well established. The aim of this study was to evaluate the evolution of symptoms after red blood cell transfusion in palliative care patients. Thirteen patients were followed at an outpatient blood transfusion clinic at the University of Campinas. Data was collected on the Palliative Performance Scale (PPS) as well as the characteristics of the patients, the oncohematological diagnosis, the stage of the disease, and clinical symptoms that justified transfusion. To analyze the evolution of symptoms and functional capacity, the Edmonton Symptom Assessment Scale (ESAS) and the Katz Index Functional Assessment Scale for basic activities of daily living were applied serially on the day of transfusion, as well as two and seven days after the procedure. We also observed the occurrence of transfusion reactions. We were able to identify improvements in symptoms such as fatigue, depression, drowsiness, as well as overall well-being in most patients up to seven days after transfusion. However, patients with seven days or more of transfusion maintained improvement only in fatigue. Similarly, other studies report an improvement in symptoms such as weakness, fatigue, and overall well-being after transfusion, this improvement also being transient and lasting less than 14 days.