Журнал исследований рака и иммуноонкологии
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Regulation of Focal Adhesions by PI(4,5)P2 and PI(3,4,5)P3 in Cancer Cell Migration

Dhurgham Al-Fahad

Title: Regulation of Focal Adhesions by PI(4,5)P2  and PI(3,4,5)P3 in Cancer Cell Migration

Name: Dhurgham Al-Fahad

Al-Ayen university, schoole of medical and health technology, Iraq

Abstract
Phosphoinositides and their downstream signalling molecules are involved in adhesion, proliferation and invasion. In this study, MDA-MB-231 breast cancer has been used to investigate the possible role of PI(4,5)P2 and PI(3,4,5)P3 in the regulation of FA turnover.

Firstly, PI(4,5)P2 and PI(3,4,5)P3 have been visualised by PLC