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Severe Rhabdomyolysis after Uneventful Long Term Low Dose Statin Therapy

Clara Frydrychowicz, Bastian Pasieka, Matthias Pierer, Wolf Mueller, Sirak Petros and Lorenz Weidhase

Rhabdomyolysis is a widely recognized yet rare complication in Statin use. Rhabdomyolysis might be triggered by prescription of high doses of Statins or by Statin accumulation due to interactions with concomitant medication. Muscle cell destruction as evidenced by myoglobin elevation can induce potentially life threatening acute renal failure known as crush kidney. Here, we report a case of a sudden severe rhabdomyolysis with consecutive renal failure in a patient who received low dose Statin- therapy for 6 years without previous complications.