Семейная медицина и медицинские исследования
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The Association Between Perception of Sensitive Skin and Objective and Subjective Measures in Women with Urinary Incontinence

Mylissa M. Trowbridge, Richard Cheng and Miranda A. Farage

Purpose: To determine the prevalence of perceived sensitive skin in urinary incontinent women, and explore associations with objective and subjective measures. Methods: A sensitive skin questionnaire was administered to 122 predominantly obese, frequent urinary incontinent women normally using protective underwear and recruited from the general population in St. Petersburg, Florida and San Antonio, Texas between October 2013 and February 2014. Their sensitive skin perception was compared with: 1) genital erythema, transepidermal water loss (TEWL) in the population, and subgroups of diabetic/menopausal status, and 2) product-related experiences. ]Results: Population of 72% postmenopausal, 82% non-diabetic women, reported overall (62%), facial (50%), genital (41%), and body (39%) skin sensitivity. No statistical differences or trends found with diabetic/menopausal profile. Sensitive skin perception corresponded to higher (worse) erythema and TEWL scores over time, with some statistically significant differences for TEWL: overall buttock site on Day 14 (p=0.02), non-diabetic buttock (p=0.03), postmenopausal buttock (p=0.01) and labia majora (p=0.03) sites at Day 7 and at the buttock (p=0.01) site on Day 14. There was a statistically discernable perceived irritation due to products used in the genital area for subjects with perceived sensitive skin (p<0.05), and sensitive skin subjects were more likely to avoid certain ingredients and look for claims related to sensitive skin (p<0.01). Conclusions: Based on this study, no association was seen between perception of sensitive skin and diabetic/ menopausal status. Skin sensitivity was associated numerically with higher (worse) erythema and TEWL scores, some reaching statistical significance. Sensitive skin consumers were more likely to experience product irritation used in the genital area, avoid certain ingredients, and look for sensitive skin claims. The diabetic population was small in this study, and a larger study is needed for final conclusion.m.