Достижения в области медицинских исследований

Достижения в области медицинских исследований
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ISSN: 2564-8942


To evaluate the efficacy and effectiveness of N-butyl 2-cyanoacrylate glue (TRU SEAL) in closure of oral, maxillofacial laceration and surgical incisions

Praveen Kumar Singh

Introduction: Effective wound closure is critical for minimizing wound complications and preventing wound dehiscence. The various wound closure techniques include staples, traditional nylon and skin sutures, subcuticular sutures and skin adhesives. Currently topical skin adhesives are frequently being used. Most of the adhesives used are cyanoacrylates short and long chain (butyl and isobutyl cyanoacrylates) derivatives. Cyanoacrylates (CAC) are tissue adhesives exhibiting the objectives of achieving coaptation of surgical wound borders, and thus eliciting healing. This material is bacteriostatic and biodegradable and exhibits suitable tensile strength. Cyanoacrylates glue results in cutaneous closure in less than 5 minutes. It should not be used for deep wound closure or in any patient sensitive to cyanoacrylates. Wound closure using tissue adhesives require careful attention to be given to closure of subcutaneous layer to ensure optimal approximation and tension on the edges of the wound. Cyanoacrylates glue polymerize rapidly within seconds following contact with proteinaceous surfaces to form strong and flexible bonds. This chemical property makes them extensively used in different surgical application. Prior to application of cyanoacrylates, the tissue surface should be cleaned and dried as much as possible. Protection of the surrounding tissues from accidental contact with cyanoacrylates can be done by covering them by gauze or chloramphenicol 1% ointment. Method: Under naso-endotracheal intubation, skin preparation was done with povidone iodine. Skin incision for each procedure was placed in the standard location. Then reduction of fracture and plating was done.In 80% of the patient