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What should be done and what not in the Management of Patient with PenisCancer: A Non-Systematic Review of the Literature

Raffaele Baio1*, Giovanni Molisso2, Umberto Di Mauro2, Oliviero Intilla2, Alessandro Pane2, Roberto Sanseverino2

Penis cancer is a rare condition in Europe, for whose onset phimosis and poor hygiene are strong risk factors. More than 95% of penile carcinomas are squamous cell carcinomas. Early disease is curable in most patients, who can be treated by conventional penile amputation or, in selected cases, by organ preserving techniques. For more advanced primary tumors, penile amputation is necessary. Survival of patients with penis cancer is strongly related to the presence and extent of nodal metastases, for the treatment of which inguinal lymphadenectomy is crucial. The role of chemotherapy, as adjuvant and neoadjuvant or primary treatment in metastatic disease, needs to be further explored in prospective clinical trials.