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A Case of Dengue Fever-Induced Severe Aplastic Anemia Salvaged by Allogeneic Bone Marrow Transplant

Lujain Khoj, Rawan Baksh, Mohammad Aslam, Mohammad Kelta, Bassim Albeirouti and Jalil Ur Rehman

Aplastic anemia (AA) is a type of bone marrow failure characterized by peripheral pancytopenia and bone marrow hypoplasia. The complications of AA include infections and bleeding. A rare association between dengue fever and AA has been reported. Dengue fever is a disease endemic to the western region of Saudi Arabia. In the literature 8 cases of Dengue fever induced Aplastic anemia has been reported and treated conservatively, but none has received allogeneic bone marrow transplant .In the context of this background, we report the first case of dengue fever–induced severe AA (SAA) salvaged by an allogeneic bone marrow transplant (BMT).