Передовые методы в биологии и медицине

Передовые методы в биологии и медицине
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ISSN: 2379-1764

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Aromatic Heterobicyclics-Based Design of Aldose Reductase Inhibitors as Drug Candidates for the Treatment of Diabetic Complications

Zhongfei Han, Nino Rcheulishvili, Dimitri Papukashvili, Xin Hao and Changjin Zhu

Aldose reductase (ALR2) plays a pivotal role in the development of diabetic complications. ALR2 inhibitors (ARIs) have proven efficient to prevent and delay the chronic diseases, and thus attracted significant research interest. This article reviews a series of aromatic heterobicyclics-based ARIs developed over recent years, and discusses about their structure-activity relationships as well as their multifunctionalities such as antioxidant property

Отказ от ответственности: Этот тезис был переведен с использованием инструментов искусственного интеллекта и еще не прошел рецензирование или проверку.
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