Журнал клинической химии и лабораторной медицины

Журнал клинической химии и лабораторной медицины
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Clinical characteristics of 82 cases of COVID-19 patients in Wuhan, China

Yue Zhu1, Kun Liu2, Jian Zhou3, Sihuan Xu1, Xin Li1, Yixun Liu4, Yongying Ding 5*, Yan Liu1*

Background: COVID-19 has become a global public health emergency. Currently, COVID-19 is still widespread in some countries. We report the epidemiological, clinical, laboratory, radiological characteristics, treatment and clinical outcomes of 82 cases of COVID-19 patients.

Methods: The electronic medical records of 82 COVID-19 hospitalized patients with confirmed SARS-CoV-2 virus infection were extracted and analyzed in detail.

Results: The median age of those patients was 61 years; 58.5% of the patients were male. The primary composite end point occurred in 63 patients (76.8%), including 3.2% who died and the rest recovered. Fever (67.1%), cough (78.1%), fatigue (50.0%), cough with phlegm (36.6%), and muscle soreness (31.7%) were the most common clinical symptoms, whereas hypertension (31.7%), heart disease(12.2%) and diabetes mellitus (7.3%) were the most common comorbidities. Ground-glass opacity was present in 71 (86.6%) patients. Lymphopenia (61.7%) and procalcitonin (65.4%), C-reactive protein (86.3%) increased were observed in most patients.

Conclusions: COVID-19 patients sometimes free of fever and cough, and many had no abnormal radiologic findings. A clinical investigation of 82 COVID-19 patients suggested that lymphopenia and procalcitonin, C-reactive protein increased may be a potential indicator for diagnosis.

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