Терапия волос и трансплантация
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Combination Therapy with Injectable Platelet Rich Fibrin (PRF) and Polydioxanone (PDO) Threads in Treatment of Male Pattern Baldness: A Novel Approach

Shashank Bansod *, Umesh Bilewar, Amit Kerure, Shaurya Rohtagi

Injectable PRF is a second generation, fully autologous biomaterial obtained from blood, having greater number of cells and their growth factors as compared to conventional (Platelet Rich Plasma) PRP. It predominantly has type-1 collagen and lymphocytes along with its cytokines. It is more cost effective, easy to prepare and requires minimal materials for its preparation. PDO threads have been used in cardiac surgeries since long and recently have been used in dermatology as a face lifting procedure. Proposed mechanisms include neocollagenosis, fibroblast proliferation and improvement in microcirculation among others. Considering the favorable properties, we combined injectable PRF therapy and PDO monofilament thread insertion into the scalp for the treatment of Androgenetic alopecia in our patients with encouraging results.