select ad.sno,ad.journal,ad.title,ad.author_names,ad.abstract,ad.abstractlink,j.j_name,vi.* from articles_data ad left join journals j on j.journal=ad.journal left join vol_issues vi on vi.issue_id_en=ad.issue_id where ad.sno_en='25477' and ad.lang_id='3' and j.lang_id='3' and vi.lang_id='3' Features of Lipid Metabolism and Level of Pro-inflammatory C | 25477
Эндокринология и метаболический синдром

Эндокринология и метаболический синдром
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ISSN: 2161-1017

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Features of Lipid Metabolism and Level of Pro-inflammatory Cytokines in Patients with Type-2 Diabetes and with Diabetic Nephropathy Depending on the Stage of Chronic Kidney Disease

Khasanova YV, Galkina AB, Nelaeva AA and Medvedeva IV

Purpose: Study of the role and relationship of lipid metabolism parameters and level of pro-inflammatory cytokines in patients with type-2 diabetes with diabetic nephropathy (DN) depending on the stage of chronic kidney disease (CKD).
Materials and methods: 240 patients with type-2 diabetes were examined in the early stages of DN and CKD.
Results: The development of DN was accompanied by an increase in the level of pro-inflammatory cytokines and impaired lipid metabolism (hypertriglyceridemia) in patients with type 2 diabetes. A negative correlation was found between the level of triglycerides (TG) and the glomerular filtration rate (GFR) (r=-0.43) and a direct relationship between the level of IL-6 and TG (r=0.48).
Findings: An increase in the level of pro-inflammatory cytokines and TG increases the risk of the development and progression of DN and CKD.

Отказ от ответственности: Этот тезис был переведен с использованием инструментов искусственного интеллекта и еще не прошел рецензирование или проверку.
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