Журнал медицинской и хирургической патологии
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Rare Benign Vascular Tumors of Unusual Location: Two Cases Report

Imane Eliahiai*, Mohammed Eljiar, Sanae Chaib, Jinane Kharmoum, Mariame Chraibi, Jihane Nuiakh, Siham Alaoui Rachidi, Houda Hamdaoui, Taha Hasni Alaoui, Ihsane Aloubi, Aymane Jbilou, Said Ait Laalim

Vascular lesions are classified according to their tumoral, malformative or reactive origin. Their clinical incidence and their frequency in pathological recruitment are also highly variable, with some lesions being rarer or even exceptional. We report the observation of 2 rare benign vascular tumors of unusual localization.

Epithelioid hemangioma is a benign rare vascular neoplasm. It is defined by the presence of well-formed vascular channels lined by epithelioid endothelial cells. Pathologically, it has a wide morphological spectrum making diagnosis difficult. In some cases, immunoreactivity anti-FOSB is important in differential diagnosis with other malignant forms, namely epithelioid hemangioendothelioma and angiosarcoma. The pathogenesis is controversial; however, several studies argue for a neoplastic origin in 48% of cases by showing a variety of gene fusions depending on the anatomical site of the tumor. We report the observation of a huge retroperitoneal epithelioid hemangioma in a 43-year-old woman, a presentation never reported in the literature.

The second observation was a 29-year-old female patient who consulted for a right chest wall mass that was painful on exertion. A large excision was performed and pathological examination of the surgical specimen confirmed the diagnosis of intramuscular hemangioma. It is a unique benign soft tissue vascular tumor characterized by an infiltrative architecture. It can occur in any skeletal muscle but lower limb muscles are the most common sites accounting for over 50%. An intra-thoracic location is reported for the first time via our observation.