Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biol
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Thyroid Antibody Associated Recurrent Spontaneous Abortion

Radhika Tirumala and Rosalind A Hayes

Background: Recurrent spontaneous abortion (RSA) remains unexplained in about 50% of cases after a
standard evaluation. A subset of unexplained RSA may be thyroid antibody associated recurrent spontaneous abortion (TAARSA).
Cases: The three cases illustrate TAARSA with elevated thyroid antibodies and a euthyroid state. Treatment with low molecular weight heparin (LMWH) and low dose aspirin (LDA) was associated with live birth.
Conclusions: A subset of previously unexplained RSA may be identified as TAARSA. Treatment may prevent
future pregnancy loss.