Журнал пробиотиков и здоровья
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Effect of the Intake of Probiotics Isolated from Human Milk in People with Gastritis and Irritable Bowel Syndrome

Josue R. Solis Pacheco, Ariana Rodriguez Arreola, Jose A. Velarde Ruiz Velasco, Jessica G. Solis Aguilar, Jesus A. Amezcua Lopez, Manuel Loera Parra, Blanca R. Aguilar Uscanga*

Background and objective: The gut microbiota is critical to human health, and can be affected by multiple factors including diet, ethnicity, use of antibiotics, geographic location, bad habits such as cigarette smoking, alcohol or junk products consumption. The gut microbiota have various functions such as vitamin production and other essential products, but an imbalance of it, could trigger various conditions associated with diseases to metabolic syndrome, as well as, gastrointestinal problems. The objective of this work was to evaluate the effect of the intake of lactic bacteria isolated from human milk, in patients with gastritis problems and irritable colon syndrome.

Methods: 10 Mexican patients with gastritis, 10 with irritable bowel syndrome and 10 healthy as control or placebos, were selected from Guadalajara, Mexico. For 3 months, the volunteers ingested capsules with L. fermentum LH01, L. reuteri LH03, and L. plantarum LH05 (109 CFU/g). All participants underwent clinical studies and nutritional evaluation. Stool samples were collected from the thirty volunteers, to determine their microbial profile and lactic acid bacteria content by identifying the strains with the Maldi-Tof analyzer.

Results and conclusions: Due to constipation problem laxative use was a common factor among people with irritable bowel syndrome. Were identified a strain of Salmonella spp, in stool of the gastritis and irritable bowel syndrome groups. A diversity of bacteria was isolated in the stool, especially species of Bacillus subtilis and Enterococcus faecium. The intake of human milk probiotics favored the health of sick patients by 85%, an improvement in the evacuations of these people was observed from the second month after having ingested the probiotics. Decrease of disinflammation of the intestines and an improvement in the general health of the patients was observed. L. fermentum LH01, L. reuteri LH03, and L. plantarum LH05 showed significant probiotic potential to improve the problems, such as, the gastritis and irritable bowel syndrome.