Органическая химия: текущие исследования
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Synthesis and Characterization of Deshydroxy Posaconazole

Ravi Kumar K, Srinivasa Reddy B, Sreenu M, Venkata Babu VV, Dilip Kumar B, Raja Sekhar S

Posaconazole is a triazole antifungal drug and used for the treatment of infections caused by fungi. During the process development of posaconazole, the process related impurity deshydroxy posaconazole was identified as a critical impurity along with the final API. The present work describes the synthesis and characterization of this deshydroxy posaconazole.