Анестезия и клинические исследования
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Transplantation of liver for end-stage disease

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Liver replacement represents the sole definitive treatment for end-stage liver disease. Medical treatment does little to improve survival; when life-threatening complications of liver failure such as encephalopathy, gastrointestinal bleeding, or uraemia develop, the 5-year survival rate .Acute varietal bleeding is a particularly ominous prognostic sign, with a hospital mortality rate similar to that of myocardial infarction. The 3-year survival isb30%, despite endoscopic and pharmacologic advances.